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Instant Download MRCPUK : SEND Questions & Answers as PDF & Test Engine

SEND
  • Exam Code: SEND
  • Exam Name: Endocrinology and Diabetes (Specialty Certificate Examination)
  • Updated: Nov 04, 2026
  • No. of Questions: 200 Questions and Answers
  • Download Limit: Unlimited
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Get an edge on your MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) journey with premium SEND practice tests from Lead2Passed. We offer 200 questions with comprehensive updates throughout 2026, giving you the exact preparation you need.

MRCPUK SEND Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Adrenal and Parathyroid/Metabolic Bone Disorders15%- Cushing's syndrome, Addison's disease, phaeochromocytoma
- Hyperparathyroidism, hypoparathyroidism
- Primary/secondary hyperaldosteronism
- Osteoporosis, osteomalacia, Paget's disease
Topic 2: Pituitary and Hypothalamic Disorders15%- Hypothalamic dysfunction
- Diabetes insipidus and SIADH
- Pituitary adenomas: prolactinoma, acromegaly, Cushing's disease
- Hypopituitarism and hormone replacement
Topic 3: Reproductive and Other Endocrine Conditions15%- Endocrine hypertension and rare syndromes
- Obesity and lipid disorders
- Polycystic ovary syndrome
- Disorders of puberty and sex development
Topic 4: Diabetes Mellitus40%- Other forms of diabetes
  • 1. Monogenic diabetes
    • 2. Pancreatic/endocrine-induced diabetes
      - Type 1 Diabetes
      • 1. Acute complications: DKA, hypoglycaemia
        • 2. Insulin therapy and delivery systems
          • 3. Pathogenesis and natural history
            • 4. Long-term microvascular/macrovascular complications
              - Type 2 Diabetes
              • 1. Epidemiology and risk factors
                • 2. Cardiovascular risk management
                  • 3. Oral and injectable non-insulin therapies
                    • 4. Gestational diabetes
                      Topic 5: Thyroid Disorders15%- Hypothyroidism and myxoedema coma
                      - Thyroid nodules and cancer
                      - Hyperthyroidism: Graves’ disease, toxic nodular disease
                      - Thyroiditis and subclinical dysfunction

                      Frequently Asked Questions About MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination)

                      The SEND exam is a core requirement for the Specialty Certificate in Endocrinology and Diabetes certification at the Specialist / Advanced level. Earning this validates your skills for credentials like MRCP(UK), CCT (Certificate of Completion of Training), CESR.

                      Candidates will face 200 (100 per paper) questions and have 360 (180 minutes per paper, 1-hour break) to complete the exam. This means you need strict time management. We strongly recommend taking timed practice tests to ensure you can maintain a steady pace without rushing when under actual exam time pressure.

                      The official examination fee is £585 (UK), £755 (International) - 2025/26 rates, and you must achieve a score of Variable scaled score (Angoff standard-setting, published post-exam) to pass. Since retaking the test requires paying the full fee again, utilizing accurate practice materials for thorough self-assessment beforehand is crucial to protect your investment.

                      Candidate requirements include: No formal prerequisite; MRCP(UK) recommended; mandatory for CCT in Endocrinology & Diabetes. Please verify all eligibility details on the official certification page before scheduling your appointment.

                      Registration is handled through official testing partners. The exam is delivered via Computer-based at global Pearson VUE test centres; no online proctoring. You can sign up here:

                      The vendor suggests following official learning paths to build a foundational understanding:

                      Once you complete your training, use the 200 practice questions from Lead2Passed to refine your exam readiness.

                      Absolutely. A free PDF demo is available for you to evaluate the quality of our questions. Once purchased, you receive 365 days of free updates. If your access expires, you can renew it at a 50% discount to keep your materials current.

                      Your SEND practice materials are delivered instantly. You can download them right away, and a copy will be sent to your email within one minute (contact support if not received in 2 hours). You can install the software on an unlimited number of computers. We also offer a 100% Money Back Guarantee: if you fail the corresponding exam within 60 days of purchase, you can claim a full refund. To apply, submit your enrollment slip and official Score Report PDF within 2 days after taking the test (processing takes up to 7 days). Note: failures within 3 days of purchase, downloaded but unattempted exams, free materials, and expired orders are excluded. The payer's name must match the candidate's name. Alternatively, you can exchange your order for two free exams of equal value and keep the original product's updates.

                      The syllabus is divided into 5 main domains. Key areas include "Reproductive and Other Endocrine Conditions" (15%), "Diabetes Mellitus" (40%), "Pituitary and Hypothalamic Disorders" (15%). For a comprehensive breakdown of all measured skills, please review the complete exam outline table provided above.

                      MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:

                      A 64-year-old man attended the diabetes clinic for annual review. He complained of very recent tingling in his feet. A monofilament was used to screen for the presence of chronic sensorimotor diabetic peripheral neuropathy.
                      What force should a monofilament deliver?

                      • A. 5 g
                      • B. 20 g
                      • C. 2 g
                      • D. 10 g
                      • E. 1 g
                      Reveal Solution  Discussion  0

                      Correct Answer: D  🗳️

                      Carbimazole is routinely used in the management of thyroid disease.
                      What does carbimazole inhibit?

                      • A. deiodinase type 1
                      • B. thyroid peroxidase
                      • C. presentation of thyroid antigens to autoreactive T cells
                      • D. sodium/iodide symporter
                      • E. thyroglobulin synthesis
                      Reveal Solution  Discussion  0

                      Correct Answer: B  🗳️

                      An 18-year-old man was referred with muscle weakness and cramps. His blood pressure was 108/60 mmHg.
                      Investigations:
                      serum sodium143 mmol/L (137-144) serum potassium2.4 mmol/L (3.5-4.9) serum bicarbonate32 mmol/L (20-28) serum magnesium0.96 mmol/L (0.75-1.05)
                      24-h urinary calcium3.6 mmol (2.5-7.5) 24-h urinary magnesium4.2 mmol (2.5-8.0)
                      plasma renin activity (after 30 min supine)6.4 pmol/mL/h (1.1-2.7) plasma aldosterone (after 30 min supine)680 pmol/L (135-400)
                      What is the most likely diagnosis?

                      • A. Gitelman's syndrome
                      • B. Liddle's syndrome
                      • C. renal tubular acidosis
                      • D. Bartter's syndrome
                      • E. syndrome of apparent mineralocorticoid excess
                      Reveal Solution  Discussion  0

                      Correct Answer: D  🗳️

                      A 25-year-old woman presented at 28 weeks' gestation after a screening 75-g oral glucose tolerance test, which had shown a fasting plasma glucose of 5.6 mmol/L (3.0-6.0) and a 2h plasma glucose of 9.8 mmol/L (<7.8). She had a family history of type 2 diabetes mellitus and a pre-pregnancy body mass index of 36 kg/m2 (18-25). Home blood glucose monitoring had shown persistently raised blood glucose despite dietary modification. She refused insulin because of needle phobia and was concerned about drug exposure to her unborn child.
                      The use of what hypoglycaemic therapy is acceptable in this situation?

                      • A. gliclazide
                      • B. pioglitazone
                      • C. glibenclamide
                      • D. exenatide
                      • E. sitagliptin
                      Reveal Solution  Discussion  0

                      Correct Answer: C  🗳️

                      A 45-year-old woman attended for annual follow-up for long-standing hypoparathyroidism (a complication of thyroid surgery 5 years previously). She was asymptomatic. She was taking alfacalcidol 1 microgram daily.
                      Examination was unremarkable.
                      Investigations:
                      serum creatinine105 umol/L (60-110)
                      serum corrected calcium2.45 mmol/L (2.20-2.60)
                      24-h urinary calcium9.8 mmol (2.5-7.5)
                      What is the most appropriate next step in management?

                      • A. decrease alfacalcidol dosage
                      • B. recommend low-calcium diet
                      • C. add bendroflumethiazide
                      • D. change alfacalcidol to calcitriol
                      • E. change alfacalcidol to teriparatide
                      Reveal Solution  Discussion  0

                      Correct Answer: A  🗳️

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